Neuroactive steroids are also called as neurosteroids . They are endogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors. Neuroactive steroid refers to steroids that are synthesized by an endocrine gland that reach the brain through the bloodstream and have effects on brain function. Neurosteroids have a wide range of potential clinical applications from sedation to treatment of epilepsy and traumatic brain injury. Ganaxolone is a synthetic analog of the endogenous neurosteroid. Allopregnanolone is under investigation for the treatment of epilepsy.
How that statement fueled the final decade-plus of Clemens's career is an issue addressed further below, but for now we'll stick to the record as it unfolded at the time. In December 1996, the Rocket signed a three-year, $ million deal with Toronto and then put together back-to-back seasons in which he won not only Cy Young awards but also Triple Crowns. His 1997 campaign (21–7, ERA, 292 strikeouts, WAR) was by far the better of the two seasons, though his WAR the following year led the league as well. That WAR season in 1998 ranks fourth among all pitchers since 1915, wins behind the totals of Alexander (1920), Carlton ('72) and Dwight Gooden ('85).
He said that midwest farmers in the US could produce lots and lots more food, and that if prices rose he would increase his production appropriately. This supports fnord’s suspicion that the Netherlands can produce a lot of high mark up items. Lots of countries could, if their customers got really into expensive foods no doubt production would dramatically increase in the US, Canada. Compared to other costs, food has become so cheap that many countries throw most of their food away and innovations in production are unnecessary. The bulk of food export costs are shortage and transportation.