Primary hypogonadism (congenital or acquired): Testicular failure due to diseases and conditions in the body such as cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter Syndrome, chemotherapy, or toxic damage from alcohol or heavy metals; these men usually have low serum testosterone levels and gonadotropins (FSH, LH) above normal range Hypogonadotropic hypogonadism (congenital or acquired): Gonadotropin or luteinizing hormone-releasing hormone (LHRH) deficiency or pituitary-hypothalamic injury from tumors, trauma, or radiation; these men have low testosterone serum concentrations but have gonadotropins in the normal or low range.
Some of the common side effects from continued use of Testosterone Propionate include gynecomastia, bloat or excess water retain, high LDL cholesterol, low HDL cholesterol and high blood pressure. The most noticeable side effect will probably be testicular atrophy. In men, testosterone is produced in the testicles. Artificial introduction of the hormone into the body means the natural production will cease since the body is receiving enough and probably excess of it. Due to suppression in the production of the hormone, the testicles shrink. The testicles regain their normal size and shape when artificial consumption is ceased.