Metabolic effects occurring during anabolic steroid therapy in immobilized patients or those with metastatic breast disease include osteolytic-induced hypercalcemia.
Anabolic steroids effect electrolyte balance, nitrogen retention, and urinary calcium excretion. Edema, with and without congestive heart failure, has occurred during anabolic steroid therapy.
The androgenic activity of anabolic steroids may decrease levels of thyroxin-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
Significant increases in low density lipoproteins (LDL) and decreases in high density lipoproteins (HDL) have occurred. [ Ref ]
It is very common for bodybuilders to use veterinary steroids for a precontest cycle. Since they are typically assimilated quickly, they do the best work in the shortest amount of time, and are generally out of the system relatively fast in comparison to other ‘roids. And, believe it or not, usually people see fewer side effects when using vet products than when using human ones. Why take anything else? Maybe not ‘why take anything else’, but why not include veterinary steroids, in one form or another, in every cycle? In my mind, veterinary drugs should really be everyone’s choice for extreme condition and definition. They combine well with androgens and other anabolics as well as any drug in the human realm of anabolic steroids. The only problem, these days anyway, is availability. You can find them in Mexico, but you risk fakes, counterfeits, lower quality, or lower dose per ml. You also, of course, face the possibility that you’ll be stopped.
There are also some who complain of joint pain when using Winstrol. As a steroid that does not aromatize there will be no water retention but the “dry feeling” may not be what many think it is. Most who use the steroid will be physique athletes or gym rats during a cutting phase. They will also typically add it into a plan late in the diet once they’re already lean. Typically, when you become very lean, bodybuilding lean, this makes the joints a little uncomfortable. With or without Winstrol this discomfort could potentially exist. As for pro athletes who have nearly every last steroid at their disposal, remember, if Winstrol weren’t effective in competitive sports so many athletes wouldn’t make it a primary and favorite choice. In fact, the combo of Winstrol with low doses of Nandrolone is a very common stack among many athletes, and this stack will greatly eliminate any potential joint discomfort should it exist.