Propionate gut

The traditional view of the gastrointestinal tract of a normal fetus is that it is sterile, although this view has been challenged in the past few years. [43] Multiple lines of evidence have begun to emerge that suggest there may be bacteria in the intrauterine environment. In humans, research has shown that microbial colonization may occur in the fetus [44] with one study showing Lactobacillus and Bifidobacterium species were present in placental biopsies. [45] Several rodent studies have demonstrated the presence of bacteria in the amniotic fluid and placenta, as well as in the meconium of babies born by sterile cesarean section. [46] [47] In another study, researchers administered a culture of bacteria orally to a pregnant dam, and detected the bacteria in the offspring, likely resulting from transmission between the digestive tract and amniotic fluid via the blood stream. [48] However, researchers caution that the source of these intrauterine bacteria, whether they are alive, and their role, is not yet understood. [49] [50]

Don’t forget that you can ingest less than 80% of your food as fat and still end up deriving over 80% of your burned calories from fat. How? You gut microbes turn fiber into saturated fat. Mostly butyrate, But also acetate, etc. This is the ketogenic diet that ruminants such as grass-fed cattle ingest. It’s all grass but they are burning mostly fat by the time the fiber gets digested. There just isn’t hardly any glucose coming out of the grass. This is the kind of ketogenic diet to aim for – high in fiber, low in small-intestine-digestible sugars and starches. Green leafy vegetables are very low on the glycemic index. You can eat a couple of pounds of this stuff a day. Start slowly though. If this hasn’t been your “keto” diet in the past, it’s worth a try. Start slowly.

Azelastine hydrochloride displayed no sensitising potential in the guinea pig. Azelastine demonstrated no genotoxic potential in a battery of in vitro and in vivo tests, nor any carcinogenic potential in rats or mice. In male and female rats, azelastine at oral doses greater than 3 mg/kg/day caused a dose-related decrease in the fertility index; no substance-related alterations were found in the reproductive organs of males or females during chronic toxicity studies, however, embryotoxic and teratogenic effects in rats, mice and rabbits occurred only at maternal toxic doses (for example, skeletal malformations were observed in rats and mice at doses of mg/kg/day).

Propionate gut

propionate gut


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