This can be countered to an extent. You can increase the dosage towards the middle and later parts of taking it to increase the positive effects. You can also take a period of time away from the drug, cycling off for a bit to give your body time to recover before getting back to it again. Be aware that the more you take a day, the less results you will get added to through the additional dosage. So for example, taking 50mg a day adds a lot. Adding 50mg a day improves the results, but not by much. Adding 50mg more for 150mg a day adds slightly more, but it is typically not worth the negative side effects to your health for only marginal improvements. Studies conducted on the drug helps to back up this assertion, postulating that 100mgs/day is perfect for Anadrol cycling.
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are
Everyone tolerates and responds differently, so your Anadrol results may be atypical. On average, men gain about 10 to 15 pounds during a recommended six-week cycle at a dose of 50mg per day. If you take more or less, your gains may also be more or less. What’s more, diet and exercise also play a vital role in your gains, so be sure to balance these things to achieve the best results. If your plan is to bulk, many bodybuilders say you should ‘eat like a horse’ – though this is the case whether you take steroids or not. It’s best to take steps to make the most from your cycle.